Shots:

• BARDA will fund ~$483M for the advancement of mRNA-1273 to FDA licensure. The funding will scale-up the manufacturing process and enables a large-scale production in 2020 while Moderna plans to hire ~150 new employees in the US to support the scale-up
• The mRNA-1273 is currently under P-I study- being conducted by NIH. The P-I study- initiated on Mar 16- 2020- has completed enrollment of the original study: 45 healthy volunteers aged 18-55 yrs in three dose cohorts (25µg- 100µg & 250 µg)
• The NIH has recently amended P-I study to include an additional six cohorts: 3 cohorts of older adults (aged 51-70yrs.) and 3 cohorts of elderly adults (aged≥ 71yrs.)- enrollment for which is ongoing. Following the safety data from P-III study- the company expects to initiate P-II study in Q2’20 and P-III study in the fall of 2020

Click here ­to­ read full press release/ article | Ref: Moderna  | Image: Moderna

Related News: NIH Initiates its P-I Trial for COVID-19 at KPWHRI in Seattle