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Astellas Collaborates with CytomX Therapeutics to Develop Probody T-Cell Engaging Bispecific Therapies for Cancer Indications

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Astellas Collaborates with CytomX Therapeutics to Develop Probody T-Cell Engaging Bispecific Therapies for Cancer Indications

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  • CytomX to receive $80M up front- ~$1.6B as pre/ clinical & commercial milestones- along with royalties on sales and will be responsible for research and discovery activities- up to clinical candidate selection
  • The companies partnered for several initial programs and will utilize CytomX’s Probody therapeutic technology for CD3 bispecific targets and its expertise in targeting multiple Ab modalities to the tumor micro-environment
  • For a specified number of targets- prior to the initiation of the first clinical study- CytomX to get an option to fund a pre-determined portion of development cost and may receive a pre-specified portion of profits in the US and royalties on sales (ex-US) and may later exercise its option for co-commercialization rights in the US

Click here ­to­ read full press release/ article | Ref: PRNewswire  | Image: Astellas


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