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Daiichi Sankyo Reports First Patient Dosing in P-III (DESTINYLung06) Trial of Enhertu + Keytruda to Treat HER2 Overexpressing Non-Squamous NSCLC

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  • Daiichi Sankyo has dosed the first patient with Enhertu in combination with Keytruda in the P-III (DESTINYLung06) trial as a 1L treatment for unresectable, LA/M HER2 overexpressing & PD-L1 (TPS<50%) non-squamous NSCLC
  • Trial will assess Enhertu (5.4mg/kg) + Keytruda vs Keytruda + Pt-based CT + pemetrexed as the 1L treatment in the mentioned pts (n=~686), evaluating PFS per BICR as the 1EP & OS as the key 2EP, while other 2EPs incl. investigator-assessed PFS, ORR, DoR per BICR & investigator, plus safety
  • Daiichi Sankyo discovered Enhertu, which is being jointly developed & commercialized by Daiichi Sankyo & AstraZeneca; based on various studies, Enhertu is approved in 85+ countries

Ref: Daiichi Sankyo | Image: Daiichi Sankyo| Press Release

Related News:- Daiichi Sankyo Reports the Health Canada’s Approval of Enhertu for HER2 Low/Ultralow Metastatic Breast Cancer (MBC)

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