Shots:

• The P-III TOURMALINE-MM2 study involves assessing of Ninlaro + lenalidomide + dexamethasone vs PBO + lenalidomide + dexamethasone in 705 transplant-ineligible patients with newly diagnosed MM
• The P-III TOURMALINE-MM2 study results: improvement in PFS (35.3 mos. vs 21.8 mos.); safety profile is consistent with the existing prescribing information
• Ninlaro is an oral proteasome inhibitor- approved in 60+ countries- including the US- EU & Japan with 10+ regulatory filing currently under review. In 2015- the US FDA has approved the triple regimen to treat patients with MM prior treated with at least one therapy

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 Ref: Takeda | Image: Takeda