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BMS Reports Results of Triple Regimen in P-III ELOQUENT-1 Study for Patients with Newly Diagnosed Untreated Multiple Myeloma

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BMS Reports Results of Triple Regimen in P-III ELOQUENT-1 Study for Patients with Newly Diagnosed Untreated Multiple Myeloma

Shots:

  • The P-III ELOQUENT-1 study involves assessing of Empliciti (elotuzumab)+ Revlimid (lenalidomide) and dexamethasone (ERd) vs Rd in transplant-ineligible patients with newly diagnosed- previously untreated MM
  • The P-III ELOQUENT-1 study resulted in not meeting its 1EPs of PFS while the safety profile of ERd is consistent with its known profiles
  • Empliciti is an immunostimulatory Ab targeting SLAMF7 and has received the FDA’s approval in 2015 as a combination therapy with Rd for MM patients prior treated with one to three therapies and in 2018 approved as EPd combination therapy for MM patients prior treated with two therapies

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Ref: BMS | Image: BMS 


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