Takeda's Entyvio (vedolizumab) Receives NMPA's Approval to Treat Moderate to Severe Active Ulcerative Colitis and Crohn's Disease
Shots:
- The NMPA has approved Entyvio to treat patients with moderately to severely active UC & CD having inadequate response to- lost response to- or were intolerant to conventional therapies or TNFα inhibitors
- In 2018- NMPA has included the therapy in the first batch list of ‘urgently needed’ overseas medicines for accelerated approval
- Entyvio (IV) is a gut-selective mAb- designed to specifically antagonize the α4β7 integrin to intestinal (MAdCAM-1) but not VCAM-1 and has received marketing authorization in 60+ countries including the US and EU
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