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• The company reported the dosing of a first healthy volunteer in a P-I study of TD-0903 and anticipates that TD-0903 has the potential to inhibit the cytokine storm associated with ALI and prevent progression to ARDS
• Earlier- Theravance has received approval to initiate the P-I study for assessing safety- tolerability and pharmacokinetics of SAD/MAD of TD-0903 in healthy volunteers and will enroll up to 54 volunteers in the UK. Following the regulatory review and approval- the program will move to P-II study in the same clinical setting
• TD-0903 is a lung-selective- nebulized pan-JAK inhibitor and showed the reduction in the signaling of multiple cytokines associated with cytokine storm syndrome in its preclinical study

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