Shots:

• The P-III CheckMate -9LA study involve assessing of Opdivo (360mg q3w) + Yervoy (1mg/kg q6w) combined with CT (two cycles) vs CT as monothx. (up to four cycles followed by optional pemetrexed maintenance therapy if eligible) as a 1L treatment in patients with advanced NSCLC regardless of PD-L1 expression and histology
• The P-III CheckMate -9LA study resulted in meeting 1EPs of superior overall survival (OS) at a pre-specified interim analysis. 2EPs includes PFS- ORR and efficacy measures according to biomarker
• Opdivo is a PD-1 immune check inhibitor harnessing the body’s own immune system to restore anti-tumor immune response while the Opdivo and Yervoy dual regimen was the first Immuno-Oncology combination to receive approval for metastatic melanoma and is approved in 50+ countries including the US & EU

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Ref: BMS | Image: BMS