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Biogen Collaborates with Stoke Therapeutics to Develop and Commercialize Zorevunersen for Dravet Syndrome

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 Biogen & Stoke Therapeutics

Biogen Collaborates with Stoke Therapeutics to Develop and Commercialize Zorevunersen for Dravet Syndrome

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  • Biogen & Stoke have partnered to develop & market zorevunersen for Dravet syndrome with Stoke retaining rights in the US, Canada, & Mexico while leading global development & Biogen securing marketing rights in other regions
  • As per the deal, Stoke will get $165M upfront, ~$385M in development & commercial milestones, & net sales-based tiered royalties, where external development will be co-funded (30% Biogen, 70% Stoke). Also, Biogen has an option to license certain future follow-on SCN1A-targeting ASOs with separate terms in its licensed regions
  • Stoke plans to initiate global P-III (EMPEROR) trial of zorevunersen in Q2’25 with readout expected in H2’27 which will potentially support regulatory filings worldwide

Ref: Biogen | Image: Biogen & Stoke Therapeutics

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Ridhi Rastogi

Ridhi is an avid secondary researcher who follows trends in the biopharmaceutical and healthcare sectors to curate engaging content for the global audience. She works as a news editor at PharmaShots and loves to read books and explore new destinations.

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