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BMS Reports Topline Data from P-II (TRANSCEND FL) trial of Breyanzi for R/R Indolent B-cell non-Hodgkin lymphoma

Shots:

  • BMS reported topline data from P-II (TRANSCEND FL) trial assessing Breyanzi in pts with r/r indolent B-cell non-Hodgkin lymphoma incl. follicular lymphoma & marginal zone lymphoma (MZL)
  • Study met its 1EP of significant ORR in the MZL cohort as well as its 2EP of CRR with durable responses & favorable safety
  • Breyanzi (CD19-directed) is a genetically modified autologous T cell immunotherapy that contains 4-1BB costimulatory domain to enhance expansion & persistence of CAR T cells

Ref: BMS | Image: BMS

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