Roche Reports Results of Perjeta (pertuzumab) Fixed Dose SC Combination Therapy in P-III FeDeriCa Study for HER2+ve Breast Cancer
Shots:
- The P-III FeDeriCa study involves assessing of Perjeta (pertuzumab) and Herceptin (trastuzumab) as FDC in SC formulation + CT (IV) vs its standard IV Infusion formulation + CT in patients with HER2-positive eBC- being treated with neoadjuvant and adjuvant setting
- The P-III FeDeriCa study results: reduction in the time spent for receiving treatment- loading dose & maintenance dose (8min. & 5min. vs 150min. & 60min.-150min.); safety profile is consistent with IV regimen respectively
- The FDC regimen combines Perjeta and Herceptin via Halozyme Therapeutics’ Enhanze drug delivery technology- which is based on rHuPH20 enzyme- work by optimizing SC drug delivery to co-administer therapies
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