Shots:

• The pooled analysis of the two P-III CheckMate -017 and -057 studies involves assessing of Opdivo (3 mg/kg- q2w) vs Docetaxel (75 mg/m²- q3w) in 854 patients in a ratio (1:1) with previously treated NSCLC across both squamous and non-squamous histologies
• The P-III studies result: @5yrs. OS (13.4% vs 2.6%); patients continued to see response (32.2% vs 0%); m-DoR (19.9 vs 5.6 mos.); no new safety signals with extended follow-up
• Opdivo is a PD-1 immune checkpoint inhibitor- harnessing the body’s own immune system to restore anti-tumor immune response and is the first PD-1 immune checkpoint inhibitor to receive regulatory approval anywhere in the world

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Ref: BMS | Image: BMS