Shots:

• AbbVie and Idera collaborated to conduct clinical study evaluating the combination of ABBV-368 + tilsotolimod + CT or ABBV-181. AbbVie will be responsible for conducting the trial while Idera to provide clinical trial supply of tilsotolimod
• The P-Ib study will evaluate the safety- tolerability- PK and preliminary efficacy of ABBV-368 plus tilsotolimod in three different arms in patients with recurrent or metastatic head and neck squamous cell carcinoma
• Abbvie’s ABBV-368 is anti-OX40 mab- being evaluated in P-I study for solid tumors. ABBV-181 is an anti-PD1 mAb- being developed in combinations with other AbbVie’s molecules for solid tumors and hematologic malignancies while tilsotolimod is a TLR-9 agonist developed by Idera for multiple cancer indications

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Ref: Idera | Image:AbbVie