Vasa Therapeutics Reports the Initiation of the P-I Trial Evaluating VS-041 for the Treatment of HFpEF
Shots:
- The company received the MHRA’s approval to initiate a FIH P-I HV trial of VS-041 (oral) for the potential treatment of heart failure with preserved ejection fraction (HFpEF)
- This P-I study will evaluate the safety, tolerability & PK of VS-041 in healthy volunteers, alongside Vasa also received a $11M seed funding led by Orphinic Scientific, i&i Biotech Fund among others
- Preclinical study co-funded by the ERDF & Polish NCRD showed, VS-041 significantly reduced cardiac fibrosis and improved diastolic heart function, preventing the release of endotrophin from primary human cardiac fibroblasts. During GLP toxicology assessments, it exhibited significant safety & tolerability.
Ref: Vasa Therapeutics | Image: Vasa Therapeutics
Related news:- Novo Nordisk Reports P-III Trial (STEP-HFpEF) Results of Semaglutide for Heart Failure with Preserved Ejection Fraction and Obesity
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