AstraZeneca Reports Results of Fasenra in BORA P-III Extension trial for the Treatment of Severe Eosinophilic Asthma

Shots:

• The BORA P-III trial involves assessing of Fasenra (benralizumab) enrolling patients in ratio (1:1) who have completed one of the two SIROCCO or CALIMA P-III trials, administering Fasenra 30 mg SC q4w or q8w
• BORA results (N= 1926): improvement in efficacy outcomes; overall annual asthma exacerbation rate (eosinophil counts of 300 cells per μL) is consistent; 74% of patients with (eosinophil counts ≥300 cells per μL) resulted in exacerbation free
• AstraZeneca’s Fasenra is a first respiratory biologic, approved in the US, EU including Japan and other countries as an add-on treatment in severe eosinophilic Asthma. It is available as FD SC injection with a prefilled syringe administered q4w for the first three doses followed by q8w

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