Regeneron’s Dupixent (dupilumab) Receives EC’s Approval as First Targeted Medicine for Severe Atopic Dermatitis
Shots:
- The EC has approved Dupixent for sev. AD in children aged 6mos. to 5yrs. The approval was based on the P-III trial evaluating Dupixent (200/300mg, q4w) + low-potency TCS vs TCS alone in 162 children aged 6mos. to 5yrs.
- The results showed that 46% vs 7% of patients achieved ≥75% improvement in overall disease severity, 14% vs 2% achieved clear or almost clear skin & 55% vs 10% reduction in overall disease severity from baseline & 42% vs 1% reduction in itch from baseline
- Improvement in sleep quality, skin pain, and health-related QoL were seen in an overall and sev. populations while long-term efficacy data showed the clinical benefit at 16wks. sustained through 52wks. The safety results were consistent with the known safety profile of Dupixent
Ref: GlobeNewswire | Image: Regeneron
Related Post:- Regeneron Presents P-III Trial Results of Dupixent (dupilumab) for Atopic Hand and Foot Dermatitis at AAD 2023
Click here to read the full press release
Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.
