Medivir AB Reports the First Patient Dosing of Fostrox + Lenvima in P-IIa Trial for the Treatment of Hepatocellular Carcinoma
Shots:
- The first patient has been dosed in the P-IIa dose-expansion portion of the P-Ib/IIa study evaluating the safety & efficacy of fostroxacitabine bralpamide (fostrox) + Lenvima (tyrosine kinase inhibitor) in ~30 patients with HCC at 14 clinics across the UK, Spain, and South Korea
- The preliminary results from the P-Ib study of fostrox + Lenvima were encouraging with a good safety and tolerability profile with no evidence of DLTs. In this combination arm, 30mg of fostrox was the RP2D
- Additionally, the P-Ib dose escalation part of the P-Ib/IIa study evaluating fostrox in combination with Keytruda (anti-PD-1 checkpoint inhibitor) is still ongoing
Ref: PRNewswire | Image: Merck
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