Prelude Therapeutics Entered into a Clinical Trial Collaboration with BeiGene to Evaluate PRT2527 + Zanubrutinib for Hematologic Cancers
- The companies collaborated to evaluate PRT2527 (CDK9 inhibitor) + zanubrutinib (BTK inhibitor) in patients with hematologic malignancies. PRT2527 is being studied as monotx. in a P-I dose-escalation study for advanced solid tumors & r/r hematologic malignancies
- BeiGene will be responsible to provide zanubrutinib to Prelude while Prelude will hold all global operational, development, and commercialization rights and responsibilities for PRT2527
- PRT2527 was highly effective in preclinical models at well-tolerated doses & decreased MCL1 and MYC protein levels in preclinical studies. In comparison to less selective CDK9 inhibitors, the treatment showed high potency & kinase selectivity which also improved efficacy and safety
Ref: Globenewswire | Image: BeiGene
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