aTyr Pharma, Efzofitimod, Systemic Sclerosis-Associated Interstitial Lung Disease, Clinical Trial, P-II Study
Shots:
- The company plans to initiate the P-II PoC study efzofitimod (270/450mg) vs PBO in a ratio (2:2:1), following the IND clearance from the US FDA. Additionally, ~25 patients will enroll with progressive disease who are currently receiving background mycophenolate therapy at multiple centers in the US
- The primary objective will be to evaluate the efficacy of multiple doses of efzofitimod (IV) on pulmonary, cutaneous & systemic manifestations & secondary objectives incl. safety & tolerability
- Efzofitimod is being studied in the P-III study (EFZO-FIT) for pulmonary sarcoidosis. The P-Ib/IIa study of efzofitimod showed safety & consistent dose-response, trends of benefit on key efficacy EPs incl. steroid reduction, lung function, clinical symptoms & inflammatory biomarkers
Ref: aTyr Pharma | Image: aTyr Pharma
Related News:- aTyr Pharma Reports the First Patient Dosing in the P-III (EFZO-FIT) Study of Efzofitimod for the Treatment of Pulmonary Sarcoidosis
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Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.
