Priothera Reports the First Patients Enrollment of Mocravimod in P-IIb/III Trial (MO-TRANS) for the Treatment of Acute Myeloid Leukemia
- The first patients have been enrolled in the P-IIb/III trial (MO-TRANS) evaluating mocravimod as an adjunctive & maintenance therapy in AML patients undergoing allogeneic HCT. The trial initiates in the EU, Israel, the US & in additional Asian & Latin American countries
- The study will be based on the pre-clinical & clinical PoC studies which showed the ability of mocravimod to improve survival outcomes for hematological malignancies requiring allogeneic HCT. The P-IIb/III trial will evaluate relapse-free & overall survival of 2 dose levels of mocravimod over PBO, results are expected in 2025
- In the P-Ib/IIa study, mocravimod was safe & well tolerated. Mocravimod, a sphingosine 1 phosphate receptor modulator showed a benefit in an early clinical study
Ref: PRNewswire | Image: Priothera
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