Sandoz Presents (REFLECT) Study Results of Riximyo (biosimilar, rituximab) Demonstrated Proven Effectivity for Large B-Cell Lymphoma at EHA 2022
Shots:
- The (REFLECT) study evaluates Riximyo vs Rituxan in patients with large B-cell lymphoma. The study was also the first postapproval trial of Riximyo + R-CHOP for CD-20+ DLBCL
- The results showed confirmed comparable safety & effectiveness profiles b/w rituximab biosimilars & Rituxan, 110 patients achieved CR & 50 with PR, ORR (94.7%), PFS @1 & 2yrs. (84.9% & 78.5%), AEs in 84.6% of patients, SAEs in 63 patients
- In a population-based analysis from Denmark, researchers used a lymphoma registry to compare the effectiveness of R-CHOP therapy using a rituximab biosimilar, 3yr. PFS for the originator & biosimilar (71.8% & 72.2%), the multivariable analysis revealed no differences in PFS or OS
Ref: The Center For Biosimilar | Image: Sandoz
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