Elpiscience Partner Compass Report Interim Results of ES104 + Paclitaxel in P-II Study for the Treatment of Biliary Tract Cancers
Shots:
- The P-II study evaluates ES104 + paclitaxel to treat patients with BTC at 4 medical centers in Korea. The company also plans to open additional sites in the US
- The study showed 42% ORR from 10 patients with PRs including 9 PRs confirmed by RECIST 1.1 and 1 PR pending confirmation, CBR (92%) from 22 out of 24 patients with a PR or SD. The therapy was well-tolerated and the preliminary safety profile was consistent with prior studies
- In pre-clinical & early clinical results, the therapy provides robust anti-tumor activity in multiple solid tumors by blocking both DLL4 & VEGF-A signaling pathways. The company has initiated the patient enrolment in the P-I/II study of ES104 to treat mCRC in China
Ref: Businesswire | Image: Elpiscience
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