Roche?s Tecentriq plus platinum-based chemotherapy reduced the risk of disease worsening or death in people with previously untreated advanced bladder cancer
- IMvigor130 is the first positive Phase III study of a cancer immunotherapy combination in previously untreated advanced bladder cancer
- Data will be shared with health authorities globally, including the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA)
About the IMvigor130 study
IMvigor130 is a multicentre, partially blinded, randomised Phase III study, evaluating the efficacy and safety of Tecentriq in combination with chemotherapy or alone versus chemotherapy alone for people with mUC who have not received prior systemic therapy for metastatic disease. It enrolled 1213 people who were randomised to receive:- Tecentriq plus platinum-based chemotherapy (gemcitabine with either cisplatin or carboplatin), or
- Tecentriq, or
- Platinum-based chemotherapy (gemcitabine with either cisplatin or carboplatin) plus placebo (control arm).