Tags : Hospitalized

Sorrento Files IND for STI-1499 (COVI-GUARD) in Patients Hospitalized with

Shots: Sorrento has filed an IND for STI-1499 in patients hospitalized with COVID-19. In preclinical studies, STI-1499 has demonstrated 100% neutralizing effect (in vitro) against the highly contagious D614G mutant strain at a low dose Additionally, animal model data confirms the neutralizing profile and high potency of Ab, expected effective dose in human to be […]Read More

Theravance Reports First Patient Dosing in a P-II Study of

Shots: The first patient has been dosed in a P-II study of TD-0903. The P-II study consists of two parts: the first part will assess the safety, tolerability, and clinical response to treatment in sequential ascending dose cohorts of hospitalized COVID-19 patients, with each patient demonstrating hypoxia being dosed for 7 days The second part […]Read More

Gilead to Initiate P-II/III Study Evaluating Remdesivir in Pediatric Patients

Shots: Gilead will begin enrollment in P-II/III clinical trial assessing the safety, tolerability, PK and efficacy of remdesivir in ~50 pediatric patients with moderate-to-severe COVID-19, including newborns through adolescents The trial will be conducted at 30+ sites in the US and EU. Remdesivir is available to pediatric patients with severe COVID-19 under our compassionate use […]Read More

Genentech Receives the US FDA’s Approval for P-III Clinical Study

Shots: The US FDA has approved the P-III clinical study assessing Actemra (tocilizumab, IV) + SOC vs PBO + SOC in adult patients hospitalized with severe COVID-19 pneumonia with its 1EPs & 2EPs as clinical status, mortality, mechanical ventilation and ICU variables Post randomization, patients will be followed for 60 days and analysis will be […]Read More