Tags : Chronic Cough

Merck Reports Results of Gefapixant (45mg) in Two P-III Studies

Shots: The two P-III studies (COUGH-1 & -2) involves assessing of gefapixant (45/15mg, bid) vs PBO in 2,044 patients with refractory or unexplained chronic cough for 12 & 24wks. respectively In both the studies, gefapixant (45 mg) resulted in reduction of objectively measured 24hrs.-cough frequency @12 & 24wks. (18.45% & 14.64%), reduction in cough frequency […]Read More

Merck & Co. Reports Results of Gefapixant (MK-7264) in Two

Shots: The two P-III studies (COUGH-1 &-2) involves assessing of gefapixant (45mg, 15mg, bid) vs PBO in 732 & 1,317 patients with refractory or unexplained chronic cough with 1EP as 24hrs. cough/hr. @12wks. and 24wks. respectively Gefapixant (45mg, bid) arm met its 1EPs i.e, decrease in 24hrs. coughs/hr. @12wks. & 24wks. while gefapixant (15mg, bid) […]Read More