Logo

Horizon Reports First Patient Enrollment in P-IIb Trial of HZN-825 for the Treatment of Diffuse Cutaneous Systemic Sclerosis

Share this

Horizon Reports First Patient Enrollment in P-IIb Trial of HZN-825 for the Treatment of Diffuse Cutaneous Systemic Sclerosis

Shots:

  • The company has enrolled the 1st patient in a P-IIb trial to evaluate HZN-825 (300mg, qd/bid) in a ratio (1:1:1) in 300 patients with dcSSc for 52wks. The study is based on the results of a P-IIa trial
  • The 1EPs of the study is the change in FVC% after 52wks. of treatment & 2EPs include HAQ-DI, and other patient and physician-reported outcome measures for efficacy assessment. Additionally, patients will be eligible to enter in a 52wks. extension trial after completing the 52wks. treatment
  • HZN-825 (PO) is a selective LPAR1 antagonist that showed early signs of clinical impact in systemic sclerosis

  Ref: Horizon | Image: Horizon

Click here to­ read the full press release 

Senior Editor

This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com

Share this article on WhatsApp, LinkedIn and Twitter

Join the PharmaShots family of 12000+ subscribers

I accept the Terms and Conditions