Shots:

• The two OLE P-III 1489 and 1490 studies assessing Biktarvy (bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg) vs dolutegravir-containing triple for the treatment of HIV-1 in treatment naïve adults
• The study demonstrated the sustained efficacy & safety profile with no treatment-emergent resistance @144wks- >98% of treatment-naïve patients achieved and maintained undetectable viral load @4yrs.; viral suppression in 48wks. OLE period
• In a subgroup analysis of patients with TDR- Biktarvy achieved comparably high levels of durable viral suppression @144 weeks among participants with and without TDR (98% vs 97%; as treated analysis)

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