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Voyager Therapeutics Provides Update on NBIB-1817 (VY-AADC) Program to Treat Parkinson Disease

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Voyager Therapeutics Provides Update on NBIB-1817 (VY-AADC) Program to Treat Parkinson Disease

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  • The P-ll RESTORE-1 study involves assessing NBIb-1817(VY-AADC) for the treatment of Parkinson's disease. Neurocrine & Voyager will closely work with FDA & DCMB to determine the next clinical trial for RESTORE-1
  • DSMB request a clinical hold- follows the IND Safety Report submit by Neurocrine Biosciences related to the observation of MRI abnormalities in some RESTORE-1 study participants and requested additional patient-level data from the trial and plans to review data in early 2021
  • NBIb-1817 is an investigational recombinant AAV serotype 2 vectors encoding the gene for human AADC help to produce AADC enzyme in brain cells & convert levodopa to dopamine

 ­ Ref: GlobeNewswire  | Image: PR Newswire

Click here to­ read the full press release 

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