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Alexion Reports Results of Ultomiris (ravulizumab-cwvz) in P-III Study in Patients with Atypical Hemolytic Uremic Syndrome (AHUS)

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Alexion Reports Results of Ultomiris (ravulizumab-cwvz) in P-III Study in Patients with Atypical Hemolytic Uremic Syndrome (AHUS)

Shots:
  • The P-III study involves assessing of Ultomiris (IV) in complement inhibitor-naïve patients with aHUS- receiving dose based on their weight varying upto 3-600 mg for 2 years
  • P-III study results: reduction in thrombocytopenia in 83.9% patients; reduction in hemolysis in 76.8% patients; improved kidney function in 58.9% patients; No case of meningococcal infection observed; safe results
  • Ultomiris (ravulizumab-cwvz) is a mAb and has received ODD from the US and EU for Paroxysmal Nocturnal Hemoglobinuria (PNH) in adults and aHUS in SC respectively
Ref: Alexion | Image: Twitter

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