Shots:

• The approval is based on results from P- Ib/II GO29365 study assessing Polivy (IV- 30 & 140mg) + BR vs BR alone in 80 DLBCL patients and P-II JO40762/P-DRIVE study that evaluated Polivy + BR therapy in 35 patients with R/R DLBCL not eligible for ASCT
• The P-II part of GO29365 study demonstrated CRR (40% vs 17.5%) at (PRA 6-8wks. after the last dose of Polivy). P-DRIVE study demonstrated 34% CRR at the PRA
• Additionally- the ongoing P-III GO39942/POLARIX study assesses the efficacy and safety of Polivy + R-CHP vs R-CHOP for untreated DLBCL

 ­ Ref: Chugai | Image: Wikipedia