GSK Reports the P-III (GLISTEN) Study Results of Linerixibat to Treat Primary Biliary Cholangitis (PBC) Patients with Cholestatic Pruritus
Shots:
- The P-III (GLISTEN) study assessed the safety & efficacy of linerixibat vs PBO to treat primary biliary cholangitis patients with cholestatic pruritus
- Study achieved its 1EP, demonstrating significantly reduced itch in PBC patients, as assessed by monthly itch score, over 24wks, with safety results aligning with previous studies. Further data analysis is underway
- Linerixibat, an IBAT inhibitor, targets cholestatic pruritus in PBC by blocking bile acid re-uptake. It has received ODD from the US FDA and EMA for the same
Ref: GSK | Image: GSK
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