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Amgen Reports P-IV (FOREMOST) Trial Results Evaluating Otezla (apremilast) for the Treatment of Early Oligoarticular Psoriatic Arthritis

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Amgen Reports P-IV (FOREMOST) Trial Results Evaluating Otezla (apremilast) for the Treatment of Early Oligoarticular Psoriatic Arthritis

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  • The study results showed that 33.9% Otezla patients achieved MDA-Joints response vs 16.0% in PBO and 70.2% Otezla patients achieved clinical disease activity in psoriatic arthritis (cDAPSA) remission or low disease activity (LDA >4 to ≤13) vs 51.8% in PBO. The results will be presented at ACR’23
  • The PBO-controlled, multicenter, randomized, double-blind, parallel-group P-IV (FOREMOST) study is to evaluate patients (n=308) for the treatment of oligoarticular psoriatic arthritis with early disease duration of 5 or fewer years
  • Otezla (apremilast) is an oral medication that selectively inhibits phosphodiesterase 4 (PDE4), a small-molecule enzyme, with a specific focus on c (cAMP)

Ref: Amgen | Image: Amgen

Related News:- Amgen Announces Positive Top-Line Results of Otezla (apremilast) from P-III (DISCREET Study) to Treat Genital Psoriasis

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Shivani Chandra

Shivani was a content writer at PharmaShots. She has a keen interest in recent innovations in the life sciences industry. She was covering news related to Product approvals, clinical trial results, and updates. We can be contacted at connect@pharmashots.com.

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