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Takeda’s Adcetris (brentuximab vedotin) Receives EC’s Approval for Previously Untreated CD30+ Stage III Hodgkin Lymphoma

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Takeda’s Adcetris (brentuximab vedotin) Receives EC’s Approval for Previously Untreated CD30+ Stage III Hodgkin Lymphoma

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  • The EC has approved Adcetris in combination with doxorubicin, vinblastine, and dacarbazine (AVD) to treat adult patients with previously untreated CD30+ Stage III Hodgkin lymphoma
  • The approval was based on the P-III trial (ECHELON-1) evaluating Adcetris (ADC directed at CD30) + AVD vs doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) in adult patients. The trial met its 1EPs of modified PFS, as well as 2EPs of OS & showed a significant improvement in OS in adult patients with previously untreated Stage III or IV classical Hodgkin lymphoma
  • The safety profile was consistent with prior studies with no new safety signals. Adcetris received marketing authorization from regulatory authorities in 70+ countries for r/r Hodgkin lymphoma and sALCL

Ref: Takeda Image: Takeda

Related News:- Seagen Highlighted German Hodgkin Study Group Presents P-III Trial (HD21) Results of Adcetris (brentuximab vedotin) for Advanced Classical Hodgkin Lymphoma

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Senior Editor

Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.

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