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Daiichi Sankyo Presents P-II Trial (HERTHENA-Lung01) Results of Patritumab Deruxtecan for EGFR-Mutated Metastatic NSCLC at WCLC 2023

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Daiichi Sankyo

Daiichi Sankyo Presents P-II Trial (HERTHENA-Lung01) Results of Patritumab Deruxtecan for EGFR-Mutated Metastatic NSCLC at WCLC 2023

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  • The P-II trial evaluating patritumab deruxtecan (5.6mg/kg) in a ratio (1:1) in patients with EGFR-mutated LA or metastatic NSCLC following disease progression with an EGFR TKI and Pt-based CT in Asia, EU, North America & Oceania
  • The results showed clinically meaningful & durable responses, confirmed ORR (29.8%), 1 CR, PR (66) & 99 cases of SD, m-DoR of 6.4mos. & DCR (73.8%), m-PFS was 5.5mos. & m-OS was 11.9mos. Efficacy outcomes were consistent across subgroups incl. a subset of 209 patients prior treated with a third-generation EGFR TKI and Pt-based CT
  • The safety profile was consistent with prior clinical trials with a low rate (7.1%) of treatment discontinuation due to TEAEs, grade ≥3 (64.9%). The results were published in the Journal of Clinical Oncology

Ref: Businesswire | Image: Daiichi Sankyo

Related news:- Daiichi Sankyo Initiates P-II Study of Patritumab Deruxtecan in Patients with EGFR-Mutated NSCLC

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Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.

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