Immutep & MSD Published New Interim Data of Eftilagimod Alpha + Keytruda (pembrolizumab) in P-II (TACTI-002) Trial as 2L Treatment of NSCLC at ELCC 2022
Shots:
- The P-II (TACTI-002) trial evaluates Immutep’s eftilagimod alpha + MSD’s pembrolizumab in 36 patients with PD-L1 unselected PD-X refractory metastatic NSCLC
- As of the data cut-off date of Jan 21, 2022, 73.7% of evaluable patients (14/19) had tumour shrinkage or tumour growth deceleration, 73% were alive @6mos. in the difficult-to-treat patient population, ORR of 5.6% (2/36) with 2 patients reporting confirmed & durable partial responses for ~9 & 23mos. , DCR of 36.1% with PFS (26%) @6mos.
- Additionally, 6 patients still under therapy in the trial, m-OS has not yet been reached, was safe & well-tolerated. The therapy also showed encouraging early signs of antitumour activity
Ref: Pharmiweb | Image: Wikipedia
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