Shire Announces FDA Approval of TAKHZYRO? (lanadelumab-flyo), a First-of-its-Kind mAb Preventive Treatment for Hereditary Angioedema
- In the pivotal study, patients taking TAKHZYRO 300 mg every 2 weeks had an 87% reduction in mean monthly attacks vs. placebo (0.26 vs. 1.97, n=27 vs. n=41)
- All secondary endpoints were met and included reduction in moderate or severe attacks and attacks requiring acute treatment
- According to an exploratory endpoint, there were patients receiving TAKHZYRO 300 mg every 2 weeks who had zero attacks during the study
- TAKHZYRO is a subcutaneous injection that took the majority of patients one minute or less to self-administer
Investor Relations | ||
Christoph Brackmann | christoph.brackmann@shire.com | +41 41 288 41 29 |
Sun Kim | sun.kim@shire.com | +1 617 588 8175 |
Scott Burrows | scott.burrows@shire.com | +41 41 288 4195 |
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Emily Bunting | emily.bunting@shire.com | +41 79 866 9703 |