With Continuous Failure Active Biotech Regains Global Rights for Laquinimod from Teva
Shots:
- Teva was assessing laquinimod since 2007- globally the drug completed three P-III studies ALLEGRO- BRAVO and CONCERTO in rrMS- P-II study ARPEGGIO in primary progressive MS and single P-II LEGATO-HD trial in Huntington’s Disease(HD)
- The P-II LEGATO-HD trial in HD fails to meet 1EP@12 mos- additionally in Dec 2017- P-II POC study of laquinimod didn’t meet 1EP and 2EP in Primary Progressive MS
- Laquinimod a qd PO selective aryl hydrocarbon receptor (AhR)- for treatment of MS and HD and is also being studied for Crohn's disease and Lupus
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