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Antios Enters into a Clinical Collaboration Agreement with Assembly Biosciences to Evaluate ATI-2173 and Vebicorvir for Chronic Hepatitis B Virus Infection

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Antios Enters into a Clinical Collaboration Agreement with Assembly Biosciences to Evaluate ATI-2173 and Vebicorvir for Chronic Hepatitis B Virus Infection

Shots:

  • The companies collaborated to evaluate the safety- PK & antiviral activity of ATI-2173- vebicorvir & TDF in an ongoing P-IIa ANTT201 trial in 10 treatment naïve or off-treatment HBeAg negative or positive patients with chronic HBV infection. The cohort is expected to start in H1’22
  • ATI-2173 has demonstrated a well-tolerated safety profile & uses an ASPIN mechanism in clinical development for combination therapy. ATI-2173 is currently being evaluated in P-II clinical development
  • In P-II trials- vebicorvir was administered with NrtI therapy & demonstrated a favorable safety profile & led to greater viral suppression of HBV DNA & HBV pgRNA over NrtI therapy alone

  | Ref: PR Newswire | Image: Inf.News

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