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BMS Reports Three-Year Data of Opdivo (nivolumab) + Yervoy (ipilimumab) in P-III CheckMate -743 Trial for 1L Treatment of Unresectable Malignant Pleural Mesothelioma

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BMS Reports Three-Year Data of Opdivo (nivolumab) + Yervoy (ipilimumab) in P-III CheckMate -743 Trial for 1L Treatment of Unresectable Malignant Pleural Mesothelioma

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  • The P-III CheckMate -743 trial evaluates Opdivo (3mg/kg- q2w) + Yervoy (1mg/kg- q6w) vs CT in 605 patients with previously untreated unresectable MPM. The results will be presented at ESMO 2021
  • The result showed an improvement in OS with a reduction in risk of death- patients were alive (23% vs 15%) @3yrs.- improvement in m-OS (18.1 vs 14.1mos.)- ORR (39.6% vs 44.0%)- patients responded (28% vs 0%)- m-DOR (11.6 vs 6.7mos.). The safety profile was consistent with previous data & no new safety signals were observed
  • The combination has been approved for unresectable MPM in 14 countries globally including the US- EU- Japan & China while other regulatory applications are under review globally

  Ref: BMS | Image: BMS 

Click here to­ read the full press release 

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This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com

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