Pregnancy is one of the most exciting and happy experiences in a woman’s life. Taking care of the mother and baby is essential throughout the pregnancy. During this period, the immune system is naturally suppressed so that the mother’s body does not reject the baby and can accommodate the growing fetus. Attack by virus/bacteria or any other pathogen during such a sensitive period is an unfavourable situation.
Pregnant women are said to be more prone to diseases and infections, so an expecting mother must do everything it takes to have excellent immunity. An expecting mother with weak immunity is at risk for infections and other conditions mentioned in the figure below.
Unwanted negative effects of low immunity during pregnancy
Increased Demand for Macronutrients & Micronutrients
During pregnancy, a woman’s macronutrient and micronutrient intake need to grow significantly. Not only the mother, but the fetus also requires them. Macronutrients including carbohydrates, proteins, and fats are needed for the proper growth of the fetus. Micronutrients include vitamins and minerals in smaller quantities. When these are not supplied in adequate quantity, pregnant women have a higher risk of falling sick.
How a Viral Infection Affects the Fetus and the Pregnancy Outcome
Viral infections that can reach the fetus by crossing the placenta might have a dangerous outcome. Even in the absence of placental transmission, the fetus could be adversely affected by the maternal immune response to the infection. There is a paucity of evidence that viral infections lead to preterm labour. Strong clinical data is indicating that children of mothers exposed to certain infectious microorganisms during pregnancy have a significantly higher risk of neurological disorders (including psychiatric disorders).
Pregnancy & Immunity
In general, our immune system is like a barrier – it protects us from illness, germs, and toxins by providing resistance to those infections. Without the body`s defence mechanism the functioning of organs and overall health can be compromised. During pregnancy, the expecting mother’s immune system is rapidly changing. The maternal immune system plays a critical role in establishing, maintaining, and completing a healthy pregnancy. There is a modulation of the immune system which leads to differential responses depending not only on the type of bacteria/virus or fungi but on the stage of the pregnancy.
Strengthen Immunity to Maintain Healthy Pregnancy:
- Moderate physical activity
- Stay hydrated
- Reduce stress
- Get enough sleep
- Eat a nutritious diet
- Dietary or supplemented intake of essential micronutrients.
Should All Pregnant Women Take Supplements?
All pregnant women have prescribed supplements such as folic acid, vitamins, and iron but those suffering from the following need additional supplementation.
- Nutrient deficiency
- Nausea & vomiting
- Dietary restrictions
- Multiple pregnancies
- Poor diet
- Genetic mutations
Supplements Considered Safe During Pregnancy
1. Vitamin C
It supports growth, bone strength, wound healing, immune system, absorption of iron.
RDA: 60 mg/day for pregnant women; 80 mg/day for lactating women.
2. Vitamin D
It keeps teeth, bones, and muscles healthy. RDA: 1000-2000 IU / day 12th week onwards.
Required for proper development of bones of the fetus and prevent osteoporosis in the mother. RDA: 1 g/ day starting from 14th week for pregnant and lactating women
During pregnancy, the mother supplies blood and oxygen to the fetus, so the demand for iron becomes twice as before to keep up with the increase in blood supply.
RDA: 35 mg/day for pregnant women; 21 mg/day for lactating women
It is responsible for the production, repair, and functioning of DNA. It also relieves symptoms of the common cold. RDA: 12 mg/day for pregnant and lactating women.
Deficiency in this mineral during pregnancy may increase the risk of chronic hypertension and premature labour. Some studies suggest that supplementing with magnesium may reduce the risk of complications like fetal growth restriction and preterm birth. RDA: 310 mg/day for pregnant and lactating women.
It is necessary for fetal growth and development especially the brain. RDA: 250 mcg /day
It decreases the risk of thyroid function abnormalities for women after pregnancy. RDA: 60 mcg/day for pregnant women; 70 mcg for lactating women.
9. Folic acid
It is required for preventing birth defects of the brain and spinal cord. RDA: 500 mcg/day for pregnant women; 300 mcg/day for lactating women
1g/ day of fresh ginger root is used to treat nausea and vomiting.
It increases glutathione in pregnant women
For maintaining a healthy gut and may reduce the risk of some infections.
To conclude, pregnancy is a dynamic state; with different mechanisms of immunity varying on the stage of pregnancy. Fighting infections and strengthening immunity is important during such a sensitive period. Nutraceuticals provide the prevention or treatment of diseases through dietary supplementation. These become highly important during pregnancy to prevent conditions secondary to nutrient deficiency. The most well-known nutritional supplements regularly prescribed in pregnancy include folic acid, iron, calcium, Vitamin D, iodine, zinc, selenium, magnesium, and also vitamin C for pregnancy and lactating mothers.
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Dr. Anish Desai is a trained Clinical Pharmacologist and Pharmaceutical Physician with 3 decades of experience in Academia, Research, and Healthcare industry with proven leadership skills, strong business acumen, and a deep understanding of the Healthcare System, including Pharmaceutical, Nutraceutical & Medical device industry. He has been recognized for driving positive change, delivering solutions, developing talent, and nurturing strong relationships with external stakeholders. Holding Senior Management Position for the last 20 years and involved in strategic decision making. ‘IntelliMed Healthcare Solutions’ is a Healthcare startup launched by him with an intent to focus on strategic medical affairs for business growth, thereby infusing science into business. IntelliMed specializes in scientific, Clinical & medical support from conceptualization/Ideation to launch.
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