Logo

AstraZeneca Reports Results of Imfinzi and Tremelimumab in P-III DANUBE Study for Unresectable Stage IV Bladder Cancer

Share this

AstraZeneca Reports Results of Imfinzi and Tremelimumab in P-III DANUBE Study for Unresectable Stage IV Bladder Cancer

Shots:

  • The P-III DANUBE study involves assessing Imfinzi as monothx. & Imfinzi + Tremelimumab vs SOC CT as a 1L treatment for patients with unresectable- Stage IV (metastatic) UC whose tumor cells express high levels (≥25%) of PD-L1 & patients regardless of their PD-L1 expression respectively
  • The P-III DANUBE study did not meet its 1EPs of OS while its safety & tolerability profile is consistent with previous studies
  • Imfinzi (durvalumab) is a mAb targeting PD-L1- blocking the interaction of PD-L1 with PD-1 and CD80- being evaluated in multiple clinical studies for LA/m-BC and earlier stages of BC

Click here ­to­ read full press release/ article 

Ref: AstraZeneca | Image: AstraZeneca


Senior Editor

This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com

Share this article on WhatsApp, LinkedIn and Twitter

Join the PharmaShots family of 12000+ subscribers

I accept the Terms and Conditions