Novartis Reports Positive Results of P-II SUSTAIN study for Crizanlizumab (SEG101) to Treat Sickle Cell Disease (SCD)
Shots:
- The P-II SUSTAIN study involves assessing of crizanlizumab 2.5/5 mg/kg vs PBO in 132 SCD patients with sickle cell-related pain crises
- P-II SUSTAIN study results: 2-4 event/yr. (40.5% vs 24.4%); 5-10 event/yr. (28.0% vs 4.2%); with HbSS genotype (31.9% vs 17.0%); with concomitant use of hydroxyurea (33.3% vs 17.5%); median annual rate (63 vs 2.98); no new safety concerns observed
- Crizanlizumab (SEG101) is an anti-P-selectin mAb indicated in prevention of vaso-occlusive crises (VOCs) with SCD- with expected FDA filling in 2019
Click here to read the full press release
This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com