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Pfizer to Discontinue Danuglipron’s Development Program for Chronic Weight Management

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  • Pfizer has discontinued the development of danuglipron (PF-06882961) as a potential therapy for chronic weight management
  • Danuglipron was evaluated in 2 P-I trials (NCT06567327 & NCT06568731), meeting key PK objectives & confirming formulation & dose with potential for strong efficacy & tolerability in P-III. However, a case of drug-induced liver injury & recent regulatory input led to discontinuation of the development program
  • Danuglipron’s (GLP-1 receptor agonist) clinical data will be presented at a future conference & published in a peer-reviewed journal 

Ref: Pfizer | Image: Pfizer

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