Shots:

• The CHMP’s positive opinion is based on five P-III studies assessing Forxiga (dapagliflozin) + Onglyza (saxagliptin) + Metformin vs the Forxiga + Metformin/Onglyza + Metformin/Glimepiride/Metformin in patients with inadequately controlled T2D
• The P-III studies results demonstrated that Qtrilmet resulted in a reduction of HbA1c and is not inferior to the combined use of insulin and metformin with or without SU in reducing HbA1c
• Qtrilmet is a combination of SGLT2 inhibitor- DPP‑4 inhibitor & metformin hydrochloride extended release and is approved under the name Qternmet XR as an adjunct to diet and exercise to improve glycemic control in adults with T2D in the US

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