Cytoki Pharma Reports Results from the P-I Study of CK-0045 to Improve Cardiometabolic Risk Factors
Shots:
- Cytoki Pharma reported results from the P-Itrial assessing the safety, tolerability & PK of CK-0045 (IL-22 analog) among healthy & otherwise healthy obese subjects
- The study verified CK-0045’s target engagement by liver & gut biomarkers with PK data supporting QW SC dosing and showed reductions in body mass, LDL cholesterol, blood insulin & insulin resistance, specifically in those with decreased insulin sensitivity; the drug was safe & well-tolerated
- The above results will form the basis of P-II PoC trials investigating CK-0045 among obese & T2D participants for further evaluation, expected to be conducted during H2’24
Ref: PR Newswire | Image: Novo Nordisk
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