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AbbVie Reports Results of Upadacitinib in Two P-III Studies for Rheumatoid Arthritis #EULAR2019

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AbbVie Reports Results of Upadacitinib in Two P-III Studies for Rheumatoid Arthritis #EULAR2019

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  • The P-III SELECT EARLY & SELECT-COMPARE study results involve assessing of Upadacitinib (15mg/30mg-qd) as monothx. & Upadacitinib + MTX (15mg- qd) vs MTX & adalimumab + MTX in patients with rheumatoid arthritis respectively
  • The P-III SELECT EARLY & SELECT-COMPARE study results: @48wks. improvement in symptoms of rheumatoid arthritis measured by ACR20/50; maintain clinical remission based on (DAS28-CRP) <2.6; presented at EULAR
  • Upadacitinib is JAK1-selective inhibitor- being evaluated in multiple P-III clinical studies for psoriatic arthritis- Crohn's disease- atopic dermatitis- and ulcerative colitis and being investigated to treat ankylosing spondylitis and giant cell arteritis

Ref: AbbVie | Image: AbbVie

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