Daiichi Sankyo and AstraZeneca Report P-II trial (DESTINY-PanTumor02) Results of Enhertu (trastuzumab deruxtecan) for HER2 Expressing Advanced Solid Tumors
- The P-II trial (DESTINY-PanTumor02) evaluating Enhertu (5.4mg/kg) in 268 patients with prior-treated LA, unresectable or metastatic HER2 expressing solid tumors not eligible for curative therapy, incl. biliary tract, bladder, cervical, endometrial, ovarian, pancreatic & rare cancers
- The trial met the pre-specified target for ORR & showed a durable response. The safety profile was consistent with that observed in other trials with no new safety signals
- The results will be presented at an upcoming medical meeting & shared with global regulatory authorities. Enhertu (5.4mg/kg) was approved in 40+ countries for unresectable or metastatic HER2+ breast cancer, based on (DESTINY-Breast03) trial results
Ref: Businesswire | Image: Daiichi Sankyo
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