Logo

AstraZeneca and the US NIAID Report Results of Fasenra (benralizumab) in P-II Study for Hypereosinophilic Syndromes (HES)

Share this

AstraZeneca and the US NIAID Report Results of Fasenra (benralizumab) in P-II Study for Hypereosinophilic Syndromes (HES)

Shots:

  • The P-II (NCT02130882) study involves assessing of Fasenra (benralizumab-30mg- q4w) vs PBO in 20 patients with HES who had at least 1-000 eosinophils/µL of blood
  • The P-II (NCT02130882) clinical study results: @12wks. reduction in absolute blood eosinophil counts >50% (90% vs 30%); @48wks.maintained reduction in eosinophil counts (74%); patients taper off other HES therapies (64%)- Published at New England Journal of Medicine
  • Fasenra (benralizumab- SC- q4w) is a mAb targeted IL-5 receptor presented at the surface of eosinophils and has also received approval for eosinophilic asthma in US- EU- Japan with FDA’s ODD for HES. Kyowa Hakko in-licensed Fasenra from AZ

Ref: AstraZeneca | Image: AstraZeneca

Click here to­ read the full press release 

Senior Editor

This content piece was prepared by our former Senior Editor. She had expertise in life science research and was an avid reader. For any query reach out to us at connect@pharmashots.com

Share this article on WhatsApp, LinkedIn and Twitter

Join the PharmaShots family of 12000+ subscribers

I accept the Terms and Conditions