Merck’s Keytruda + Chemotherapy Receive EU’s Approval for Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC)

 Merck’s Keytruda + Chemotherapy Receive EU’s Approval for Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC)

Merck’s Keytruda + Chemotherapy Receive EU’s Approval for Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC)

Shots:

  • The approval is based on P-III KEYNOTE-407 study assessing Keytruda + carboplatin/nab paclitaxel vs carboplatin/nab paclitaxel monothx. in ratio (1:1) in patients with msqNSCLC regardless of PD-L1 expression 
  • The P-III KEYNOTE-407 results: ORR (58% vs 38%); mDOR (7.7mos. vs 4.8mos.); improves PFS with reduction in death (44%), improvement in OS (36%)
  • Keytruda (pembrolizumab) 200mg IV is a mAb, used as an anti-D-L1 therapy that blocks the interaction between PD-1 and its ligands i.e PD-L1 & PD- L2, further activating T lymphocytes and has received FDA’s approval for the same indication on October 30, 2018

Click here to read full press release/ article | Ref: Merck | Image: Twitter

Vartika Singh

Vartika Singh is a content writer who loves to write research articles and reports at PharmaShots. She has in-depth knowledge of the life sciences industry including the Pharma and Biotech sectors. Any articles written by her can be contacted at connect@pharmashots.com.

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